6-HO-DET

6-HO-DET
臨床資料
其他名稱	6-HO-DET; 6-OH-DET; 6-HDET; 6-Hydroxydiethyltryptamine; 6-Hydroxy-N,N-diethyltryptamine
给药途径	肌肉注射
藥物類別	Serotonergic psychedelic; Hallucinogen
ATC碼	未分配;
藥物動力學數據
藥效起始時間（英语：Onset of action）	1 hour
作用時間	3–4 hours
识别信息
	IUPAC命名法 3-[2-(diethylamino)ethyl]-1H-indol-6-ol; ;
CAS号	1476-59-1
PubChem CID	124708066;
ChemSpider	103872145;
化学信息
化学式	C14H20N2O
摩尔质量	232.33 g·mol−1
3D模型（JSmol）	交互式图像;
	SMILES CCN(CC)CCC1=CNC2=C1C=CC(=C2)O;
	InChI InChI=1S/C14H20N2O/c1-3-16(4-2)8-7-11-10-15-14-9-12(17)5-6-13(11)14/h5-6,9-10,15,17H,3-4,7-8H2,1-2H3; Key:BOLBZNHQIHKGON-UHFFFAOYSA-N;

6-HO-DET或6-羟基-DET是一种有机化合物，化学式为C₁₄H₂₀N₂O，化学名为6-羟基-N,N-二乙基色胺，或可作为迷幻药。^[1]^[3]它是二乙基色胺（DET）的重要代谢产物。^[1]^[3]

动物实验表明，它对啮齿动物产生的行为影响比DET强得多。^[4]它的log P计算值为3.1。^[5]与之对比，6-HO-DMT的log P计算值为2.4，^[6]4-HO-DET的值为2.7。^[7]

参考文献

^ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Shulgin, Alexander; Shulgin, Ann (September 1997). TiHKAL: The Continuation. Berkeley, California: Transform Press. ISBN 0-9630096-9-9. OCLC 38503252.
^ ^2.0 ^2.1 ^2.2 Szara, Stephen; Hearst, Eliot (1962). "The 6-Hydroxylation of Tryptamines Derivatives: A Way of Producing Psychoactive Metabolites". Annals of the New York Academy of Sciences. 96 (1): 134–141. doi:10.1111/j.1749-6632.1962.tb50108.x. ISSN 0077-8923.
^ ^3.0 ^3.1 Shulgin AT. Psychotomimetic Agents. Gordon M (编). Psychopharmacological Agents: Use, Misuse and Abuse. Medicinal Chemistry: A Series of Monographs 4. Academic Press. 1976: 59–146. ISBN 978-0-12-290559-9. doi:10.1016/b978-0-12-290559-9.50011-9.
^ Kalir A, Szara S. Synthesis and pharmacological activity of alkylated tryptamines. J Med Chem. May 1966, 9 (3): 341–344. PMID 5960901. doi:10.1021/jm00321a017.
^ 3-(2-(Diethylamino)ethyl)-1H-indol-6-ol. PubChem. [5 November 2025].
^ 3-(2-(Dimethylamino)ethyl)-1H-indol-6-ol. PubChem. [5 November 2025].
^ 4-Hydroxy-N,N-diethyltryptamine. PubChem. [5 November 2025].