7-乙酰氧基帽柱木碱

7-乙酰氧基帽柱木碱
识别信息
	IUPAC命名法 methyl (E)-2-[(2S,3S,7aS,12bS)-7a-acetyloxy-3-ethyl-8-methoxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate; ;
CAS号	174418-81-6
PubChem CID	11015924;
化学信息
化学式	C25H32N2O6
摩尔质量	456.54 g·mol−1
3D模型（JSmol）	交互式图像;
	SMILES CC[C@@H]1CN2CC[C@]3(C(=NC4=C3C(=CC=C4)OC)[C@@H]2C[C@@H]1/C(=C\OC)/C(=O)OC)OC(=O)C;
	InChI InChI=1S/C25H32N2O6/c1-6-16-13-27-11-10-25(33-15(2)28)22-19(8-7-9-21(22)31-4)26-23(25)20(27)12-17(16)18(14-30-3)24(29)32-5/h7-9,14,16-17,20H,6,10-13H2,1-5H3/b18-14+/t16-,17+,20+,25+/m1/s1; Key:RJTCCQKAKCMBTR-XBULZMPJSA-N;

7-乙酰氧基帽柱木碱（英語：7-Acetoxymitragynine）是一种有机化合物，分子式C₂₅H₃₂N₂O₆，为卡痛树中的生物碱 7-羟基帽柱木碱的半合成衍生物，可由其与乙酸酐合成^[1]^[2]^[3]^[4]^[5]。

参考文献

^ Takayama H, Ishikawa H, Kurihara M, Kitajima M, Aimi N, Ponglux D, Koyama F, Matsumoto K, Moriyama T, Yamamoto LT, Watanabe K, Murayama T, Horie S. Studies on the synthesis and opioid agonistic activities of mitragynine-related indole alkaloids: discovery of opioid agonists structurally different from other opioid ligands. Journal of Medicinal Chemistry. April 2002, 45 (9): 1949–1956. PMID 11960505. doi:10.1021/jm010576e.
^ Takayama H. Chemistry and pharmacology of analgesic indole alkaloids from the rubiaceous plant, Mitragyna speciosa. Chemical & Pharmaceutical Bulletin. August 2004, 52 (8): 916–928. PMID 15304982. doi:10.1248/cpb.52.916.
^ Raffa RB, Beckett JR, Brahmbhatt VN, Ebinger TM, Fabian CA, Nixon JR, Orlando ST, Rana CA, Tejani AH, Tomazic RJ. Orally active opioid compounds from a non-poppy source. Journal of Medicinal Chemistry. June 2013, 56 (12): 4840–4848. PMID 23517479. doi:10.1021/jm400143z.
^ Raffa RB (编). Kratom and Other Mitragynines. 2014. ISBN 978-1-4822-2519-8. doi:10.1201/b17666.
^ Sakamoto J, Kitajima M, Ishikawa H. Asymmetric Total Syntheses of Mitragynine, Speciogynine, and 7-Hydroxymitragynine. Chemical & Pharmaceutical Bulletin. 2022, 70 (9): 662–668. PMID 36047237. doi:10.1248/cpb.c22-00441. 已忽略未知参数|article-number= (帮助)