JM-1232

JM-1232
识别信息
	IUPAC命名法 (3R)-3-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-2-phenyl-3,5,6,7-tetrahydrocyclopenta[f]isoindol-1-one; ;
CAS号	1013427-48-9
PubChem CID	17755150;
ChemSpider	26231036 ;
UNII	MD92F5Z441;
CompTox Dashboard (EPA)	DTXSID201029752 ;
化学信息
化学式	C24H27N3O2
摩尔质量	389.50 g·mol−1
3D模型（JSmol）	交互式图像;
	SMILES O=C1C2=CC3=C(C=C2[C@H](N1C4=CC=CC=C4)CC(N5CCN(CC5)C)=O)CCC3;
	InChI InChI=1S/C24H27N3O2/c1-25-10-12-26(13-11-25)23(28)16-22-20-14-17-6-5-7-18(17)15-21(20)24(29)27(22)19-8-3-2-4-9-19/h2-4,8-9,14-15,22H,5-7,10-13,16H2,1H3/t22-/m1/s1 ; Key:MBGOHVUPIPFVMM-JOCHJYFZSA-N ;

JM-1232是一种含氮有机化合物，化学式C
24H
27N
3O
2，属于非苯二氮䓬类鎮靜药物，可用作麻醉藥^[1]^[2]，由日本丸石制药（日语：丸石製薬）株式会社的团队研发^[3]。

参考文献

^ Kanamitsu N, Osaki T, Itsuji Y, Yoshimura M, Tsujimoto H, Soga M. Novel water-soluble sedative-hypnotic agents: isoindolin-1-one derivatives. Chemical & Pharmaceutical Bulletin. December 2007, 55 (12): 1682–1688. PMID 18057740. doi:10.1248/cpb.55.1682 .
^ Nishiyama T, Chiba S, Yamada Y. Antinociceptive property of intrathecal and intraperitoneal administration of a novel water-soluble isoindolin-1-one derivative, JM 1232 (-) in rats. European Journal of Pharmacology. October 2008, 596 (1–3): 56–61. PMID 18708047. doi:10.1016/j.ejphar.2008.07.054.
^ EP 1566378,Toyooka K, Kanamitsu N, Yoshimura M, Kuriyama H, Tamura T,「Isoindoline Derivative」,发行于15 August 2012,指定于Maruishi Pharmaceutical Co Ltd.