格氏反應
格氏反應是一種有機金屬化學反應，該反應需在無水條件下將碳烷基、烯丙基、乙烯基或芳基鹵化鎂（格氏試劑）加成至醛或酮的羰基上[1][2]。此反應對碳-碳鍵的形成具有重要意義[3][4]。
參考文獻
[編輯]- ^ Smith, Michael B.; March, Jerry, Advanced Organic Chemistry: Reactions, Mechanisms, and Structure 6th, New York: Wiley-Interscience, 2007, ISBN 978-0-471-72091-1
- ^ Ouellette, Robert J.; Rawn, J. David, Ouellette, Robert J.; Rawn, J. David , 編, 15 - Alcohols: Reactions and Synthesis, Organic Chemistry (Boston: Elsevier), 2014-01-01: 491–534 [2023-11-06], ISBN 978-0-12-800780-8, doi:10.1016/b978-0-12-800780-8.00015-2
- ^ Shirley, D. A. The Synthesis of Ketones from Acid Halides and Organometallic Compounds of Magnesium, Zinc, and Cadmium. Org. React. 1954, 8: 28–58.
- ^ Huryn, D. M. Carbanions of Alkali and Alkaline Earth Cations: (ii) Selectivity of Carbonyl Addition Reactions. Trost, B. M.; Fleming, I. (編). Comprehensive Organic Synthesis, Volume 1: Additions to C—X π-Bonds, Part 1. Elsevier Science. 1991: 49–75. ISBN 978-0-08-052349-1. doi:10.1016/B978-0-08-052349-1.00002-0.