5-MeO-pip-T

5-MeO-pip-T
臨床資料
其他名稱	5-Methoxy-pip-tryptamine
藥物類別	Serotonin receptor modulator; Selective serotonin 5-HT1A receptor agonist
ATC碼	未分配;
识别信息
	IUPAC命名法 5-methoxy-3-(2-piperidin-1-ylethyl)-1H-indole; ;
PubChem CID	10467710;
ChemSpider	8643121;
ChEMBL	ChEMBL292921;
化学信息
化学式	C16H22N2O
摩尔质量	258.37 g·mol−1
3D模型（JSmol）	交互式图像;
	SMILES COC1=CC2=C(C=C1)NC=C2CCN3CCCCC3;
	InChI InChI=1S/C16H22N2O/c1-19-14-5-6-16-15(11-14)13(12-17-16)7-10-18-8-3-2-4-9-18/h5-6,11-12,17H,2-4,7-10H2,1H3; Key:QVWFRPYLSDUCFB-UHFFFAOYSA-N;

5-MeO-pip-T又称5-甲氧基-pip-色胺（化学式：C
16H
22N
2O）是一种血清素受体调节剂和选择性血清素 5-HT_1A受体激动剂。^[1]^[2]它对血清素5-HT_2A受体具有亲和力（K_i = 160–230 nM）而对血清素5-HT_2C受体没有亲和力（K_i = >10,000 nM）。^[2]

参考文献

^ Shulgin A, Shulgin A (September 1997). TiHKAL: The Continuation. Berkeley, California: Transform Press. ISBN 0-9630096-9-9. OCLC 38503252.
^ ^2.0 ^2.1 Glennon RA, Dukat M, el-Bermawy M, Law H, De los Angeles J, Teitler M, et al. (June 1994). "Influence of amine substituents on 5-HT2A versus 5-HT2C binding of phenylalkyl- and indolylalkylamines". Journal of Medicinal Chemistry. 37 (13): 1929–1935. doi:10.1021/jm00039a004. PMID 8027974.

外部链接

5-MeO-pip-T - Isomer Design

[TiHKAL-1] Shulgin A, Shulgin A (September 1997). TiHKAL: The Continuation. Berkeley, California: Transform Press. ISBN 0-9630096-9-9. OCLC 38503252.

[Glennon_1994-2] 2.0 ^2.1 Glennon RA, Dukat M, el-Bermawy M, Law H, De los Angeles J, Teitler M, et al. (June 1994). "Influence of amine substituents on 5-HT2A versus 5-HT2C binding of phenylalkyl- and indolylalkylamines". Journal of Medicinal Chemistry. 37 (13): 1929–1935. doi:10.1021/jm00039a004. PMID 8027974.

[1]

[2]